clear the way as it were, for a consideration of the sonerete sazes the main points
of which are given in the detailed table appended to these papers,
58
As is well knew the basillus may persist for a long time in dust, in dried sputum,
in urine, and so forth. When one soon how large a number of patients exhibit signs
of tuberculosis after death, several of whom showed no marked signs during life, ni
when,na we know, the basilli are shed broadenst not only in the sputum birt in the
fine spray of sofghing and mooning songmptives, the oppertunities for the organim
to gain entrance and to prepagate are many, Thus, the basillus has bem found in
the sweepings of rooms (Manfredi at, Naplos, Karpmann at Leipzig),em fruit exposed for
sale (Schairer),in the wards of hospitals (Strauss, Le Noir),in books,in the bodies
of flics (Nuttall, André),en slethos (Josyphsen, Nétel, Chaussé),as quoted by Étienne
Burnet. *On trouve some une qulatossmes des poussières atmosphèriques dans ses
poussières fixes que l'en pompe par le vide 'vasım eleanor); aves elle s'est déposó
se qu'il y a de plus léger dans so que soulèvent nes semelles que l'intomas cireula-
tion de nos russ, et es que eraehe me population malheureusmet treș ingeusiante.
As gated by Delépine the difficulties of slucidating the causes of an infestisus
disease depend on the fact that we must take nessunt of the various ways in which
the predisposing and determining fasters have sombined in thair setion, and the dif-
ficulties are increased when we attempt to assign to ouch its appropriate share. He
groups these factors under the following hosds: 1„Bistribution and habits of the
pathogeie organism. 2.Conditions influmeing its number. 3.The pathermisity and
toxicity of it,ör,in other words, the senditions influmeing its virulence. 4. The
opportunities which the organim may have of gaining assess to one or more channel, ■
of infection. 5. The conditions influmeing the resistance which any possible host
may be capable of opposing to the attacks of the organism. 6.The frequency and de-
This comes inte gree of completeness of recovery from escult er manifest infection.
play more with regard to the question of adult tuberculosis, whereas the present in-
vestigation is consemned with the disease an found in children.
Of these fasters these of spesial importance are the number and virulmes of the organim on the one side and the degree of resistance which the subjest attasked
may be able to oppose on the ather,
There appears to be no doubt that the resistanse set up,if not adequate for the destruction of the organim, even sentributes indirectly to an increase in the viru- lmes of the latter. Thus, an organim,o,g, the bacillus tuberculosis of redused vir- ulenes in milk, after inssulation was found to gain in virulenes asserding as the
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